Similarity Matrix of Proteins
Today, protein sequence comparison is the most powerful tool in computational biology for characterizing protein sequences because of the enormous amount of information that is preserved throughout the evolutionary process. SIMAP is a public database of pre-calculated protein similarities that plays a key role in many bioinformatics methods. It contains about all currently published protein sequences and is continuously updated. The computational effort for keeping SIMAP up-to-date is constantly increasing. Please help to update SIMAP by calculating protein similarities on your computer. The computing power you donate supports manifold biological research projects that make use of SIMAP data.

About SIMAP - Similarity Matrix of Proteins

Join SIMAP - Similarity Matrix of Proteins

  1. Read our rules and policies
  2. Check the system requirements
  3. Read the introduction
  4. Create your account
  5. Download, install and run the BOINC software. When prompted, enter the URL http://boinc.bio.wzw.tum.de/boincsimap
  6. If having an old (non-SSE) CPU or running UNIX: download the SIMAP and HMMER applications

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BOINCSIMAP is a periodic project that usually has work for a few days at the beginning of each month.

Project status
The project has currently no work (see below).
The similarity matrix of the SIMAP project is currently up to date. All workunits from the last calculation period are distributed, thanks to all users for chrunchig them.
The calculation of new simap workunits containing the novel proteins from March 2010 (simap app) and their domains (hmmer app) will start around April 1st, 2010.

Software status
PCs with SSE support (all modern PCs and notebooks):
 simap 5.10 for Windows stable
 simap 5.12 for Windows64 stable
 simap 5.11 for Linux stable
 hmmer 5.09 for Windows stable
 hmmer 5.09 for Linux stable
PowerPC/Intel based Apple computers (Mac's):
 simap 5.10 for MacOS >=10.3.9 stable
 hmmer 5.09 for MacOS >=10.3.9 stable
PCs without SSE (e.g. PII, K6, early Athlons):
 i386-simap** 5.10 for Windows stable
 i386-simap** 5.11 for Linux stable
PC/PARISC/IA64/Alpha/Sparc platforms for UNIX:
 UNIX simap** 5.10 stable
 UNIX hmmer** 5.09 stable

** These applications need manual installation.

Server status
Web server: ok
File server: ok
Database server: ok
User of the day

User profile Profile GPV_FR
Hi, I'm a French guy, born a couple of months before the first Space trip of a Man. I'm system manager for an european Oil company. Living in east of...
News (Deutsche Übersetzung)

New Workunits in the evening (UTC) of March 1
New Workunits: the calculation of similarities and features of new sequences, that were imported from protein databases into SIMAP until the end of February, will start in the evening (UTC) of March 1. 28 Feb 2010 7:54:38 UTC · Comment

New Workunits in the morning (UTC) of Januar 31
New Workunits: the calculation of similarities and features of new sequences, that were imported from protein databases into SIMAP until the end of January, will start in the morning (UTC) of January 31. 30 Jan 2010 14:42:43 UTC · Comment

New Workunits in the evening (UTC) of Januar 7
New Workunits: the calculation of similarities and features of new sequences, that were imported from protein databases into SIMAP until the end of December, will start in the evening (UTC) of January 7. 7 Jan 2010 5:50:37 UTC · Comment

Best wishes for 2010
The BOINCSIMAP team wishes all partipants a merry xmas and a happy new year. Thank you for supporting our project and helping to keep the largest database of protein similarities and protein features up-to-date. 23 Dec 2009 0:00:00 UTC · Comment

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Copyright © 2010 Genome Oriented Bioinformatics - TU Munich